STEREOCHEMISTRY AND MECHANISM OF THIAZOLIDINONE FORMATION

Abstract

Thiazolidinones are heterocyclic compounds that exhibit a wide range of biological activities, making them valuable building blocks in medicinal chemistry. This comprehensive investigation focuses on the stereochemistry and mechanism of thiazolidinone formation, aiming to provide a deeper understanding of their stereochemical features and the underlying reaction pathways involved in their synthesis.Thiazolidinone formation involves the condensation reaction between a thiol and an α,β-unsaturated carbonyl compound