Structure - Fungicidal Activity Relationship Of Cellulase Enzymes From Aspergillus niger
Abstract
Antifungal potential of two potent fungicides m-dinitrobenzene (MDB) and pentachloro phenol (PCP) was studied on cell wall degrading enzymes of Aspergillus niger. The structure- fungicidal activity relationship was investigated by studying the effect of different nitrobenzenes and also of various chlorinated phenols and their derivatives on cellulase enzyme activity. MDB was much more effective in inhibiting the activity of enzyme than o- and p- dinitrobenzenes of similar concentrations (i.e., 1.5 × 10-3 M). On the other hand, it was observed that the fungicidal activity of chlorophenols increases as the degree of chlorination increases. Accordingly, pentachloro phenol is much more active than mono, di, tri, or tetra chlorophenols. Lauryl PCP caused the greatest inhibition of Cellulolytic activity.
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