MODERN ASPECTS OF PREDICTION AND TREATMENT OF ENDOMETRIAL HYPERPLASIA IN THE PERI-MENOPAUSAL PERIOD.
Keywords:
In peri- and postmenopausal women, pathological processes in the endometrium are most often asymptomatic, but the risk of malignant neoplasms is higher than the general population indicators, especially in the presence of bleeding and ongoing relapses of pathological processes in the endometrium.Abstract
Hyperplastic processes of the endometrium (HPE) are the most common pathology in gynecology, especially in women in perimenopausal age and are of significant value in the biomedical and socio-economic problem. According to many authors, almost 50-60% of women of late reproductive age and in the period of perimenopause suffer from HPE. The significant clinical significance of HPE lies in the fact that they are one of the main causes of uterine bleeding in women aged 35-55 years and their hospitalization. Another reason for the close attention to HPE is the possibility of their malignant transformation, since atypical hyperplasia progresses to invasive cancer with a frequency of up to 50% of cases. The above risk of developing malignancy of glandular hyperplasia and endometrial polyposis occurs in 4-5% and can reach up to 10% in peri-postmenopause. According to many authors, atypical hyperplasia progresses to invasive cancer with a frequency of up to 50% of cases. In this article, we decided to give opinions on this issue from all sides.
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